Main
Shaun Porwal
Education
Icahn School of Medicine at Mount Sinai
Master’s in Biomeidcal Data Science
New York, NY
2021-2019
Relevant Coursework:
Bioinformatics Capstone, Biomedical Software Engineering, Introduction to Algorithms, Machine Learning for Biomedical Data Science, Rigor & Reproducibility, UNIX/Linux Fundamentals, Scientific Programming in Python 3
Rutgers University - School of Engineering
Bachelor’s in Biomedical Engineering & Chinese (double major)
New Brunswick, NJ
2019-2014
Professional Experience
Surgery Feedback/Biostatistics Data Analyst
Memorial Sloan Kettering Cancer Center
New York, NY
Present - March 2021
- Performed statistical analyses (survival, landmark, parametric, non-parametric) in R on onocological datasets and wrote reports for publications
- Developed Python package dcurves and created site for Decision Curve Analysis (DCA)
- Create pipelines from raw surgery data to web application for presenting surgical feedback to providers
Bioinformatics Research Intern
Sema4
Stamford, CT
February 2022 - February 2021
- Performed structural variant (SV) detection on over 100 BAM files, each exceeding 100GB, using tools such as Delly, SvABA and DRAGEN by Illumina
- Developed pipelines with Bash, Python, WDL, and AWS to automate SV detection and comparison across multiple algorithms
- Investigated repeat variants within 114 samples, leading to potential therapeutic approaches to diabetes
- Visualized data using various methods including Circos plots, stacked bar plots, heat maps, scatter plots, etc
- Consistently updated scripts and files on group GitHub repo to foster collaboration
Senior Design Project Lead
Rutgers University - Cai Lab
New Brunswick, NJ
June 2019 - September 2018
- Used RNA-seq pipeline for differential gene expression from multi-timepoint samples
- Developed algorithm to analyze time-series gene expression using Matlab/Linux through K-Means clustering
- Created MATLAB GUI to visualize time-series gene expression
Inorganic Manufacturing Associate
SPEX CertiPrep Group LLC Metuchen, NJ
May 2019 - May 2018
- Verified chemical standard concentrations for quality assurance, manufacturing, and packaging of inorganic standard through wet-lab techniques and analyses
- Programmed Hudson automated pipettor robot for serial dilutions & inorganic standard synthesis
- Automated crucible weight retrieval, weight averaging, and gravimetric calculations using Excel
- Organized company performance data in Excel using pivot tables and charts to support team leaders’ decision-making
Research Intern
National Taiwan University - Chen Laboratory Taipei, Taiwan
August 2017
- Presented novel research ideas to explore mutagenic DNA SDP sites and investigated gene NR2B’s neurological significance in Chinese
- Conducted RNA extraction, RT-PCR, TA Cloning, In Situ Hybridization to trace Lumbrokinase expression in A. Viride
Research Assistant
Princeton University Princeton, NJ
September 2017 - May 2017
- Developed algorithms in MATLAB and Java to search mice genome to locate self-depurinating sequences in DNA
- Conducted an independent project to trace effects of self-depurination mechanism in genome sequences to determine its relevance to site-directed self-mutagenesis
Quality Control Intern
Tokyo Chemical Industry Co., Ltd Saitama, Japan
July 2016 - June 2016
- Worked in a team to complete 5 or more QA forms/specs daily
- Trained for 160 hours in instrumentation (GC, HPLC, NMR, IR) and wet-lab techniques (Appearance, Solubility, MP, Titration, etc)
Publications
Please see Google Scholar
Pellegrino F, Tin AL, Martini A, Vertosick EA, Porwal SP, Stabile A, Gandaglia G, Eastham JA, Briganti A, Montorsi F, Vickers AJ. Prostate-specific Antigen Density Cutoff of 0.15 ng/ml/cc to Propose Prostate Biopsies to Patients with Negative Magnetic Resonance Imaging: Efficient Threshold or Legacy of the Past? Eur Urol Focus. 2023 Mar;9(2):291-297. doi: 10.1016/j.euf.2022.10.002. Epub 2022 Oct 19. PMID: 36270887.
Pellegrino F, Tin AL, Sjoberg DD, Benfante NE, Weber RC, Porwal SP, Briganti A, Montorsi F, Eastham JA, Laudone VP, Vickers AJ. The effect of the da Vinci® Vessel Sealer on robot-assisted laparoscopic prostatectomy complications. J Robot Surg. 2023 Apr 12. doi: 10.1007/s11701-023-01595-x. Epub ahead of print. PMID: 37043122.